Mouse Anti-Tomato ide Antibody (MO-AB-34671H)


Cat: MO-AB-34671H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityTomato (Lycopersicon esculentum)
CloneMO34671C
SpecificityThis antibody binds to Tomato ide.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
Product OverviewThis product is a mouse antibody against ide. It can be used for ide detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesInsulin degrading enzyme; ide
UniProt IDQ93YG9
Protein RefseqThe length of the protein is 971 amino acids long.
The sequence is show below: MAVGKKEENMAVEIVKPRIDKRDYRRIVLQNNLEILLISDPETDKCAASMNVCVGAFSDPEGLEGLAHFLEHMLFYASEKYPVEDSYSKYITENGGSTNAFTSSEDTNYYFEVNADGFEEALDRFAQFFIKPLMSADATTREIKAVDSEHQKNLLSDPWRMNQLQKHLSAENHPYHKFSTGSWDTLEVRPKERGIDTRQELLKFYSENYSANLMHLVVYSKDSLDKVEQLVRGKFQDIRNIDRNQIHFTGQPCIMEHLQILVRAVPIKQGHKLKIIWPITPGIHHYKEGPCRYLGHLIGHEGEGSLFYVLKKLGWATSLSAGESDWTNEFSFFKVAIDLTDAGQDHFEDIMGLLFKYIHLLQQAGASKWIFEELSAICETAFHYQDKIRPSDYVVNVAMNMQHYPPEDWLVASSLPSKFNPSIIQSFLNELNPDNVRIFWESTKFEGNTSMTEPWYGTAYSIEKVGGDSIKQWMEHAPSEELHLPAPNVFIPTDLSLKPVFEKTKVPILLRKSPYSRLWYKPDTAFSSPKAYVMIDFSCPYCGHSPEAEVLTEIFTRLLMDYLNEYAYNAQVAGLYYDISKTNSGFQLTLFGYNDKLRVLLEAVIEKVAKFEVKPDRFSVVKELVTKQYQNFKFQQPYQQVMYYCSLLLKDNIWPWNEELDVLPHLKVDDLVKFYPLLMARSFMECYVAGNVEQAEAESMIQLIEDVFFKGPQSISKPLFASQHLTNRVVNLERGVNYVYAAEGLNPSDENSALVHYIQVHQDDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYITVLMQRSDSGVHGVQFIVQSTAKDPKYIDTRVELFMKMFESKLYEMTSDEFKNNVNALIDMKLEKHKNLREESRFYWREISDGTLKFDRRDREIVALKQLTQKELTDFFDEYIKVGVPRKKALSVRVYGSSHSSQFQAHKNEQMEPNAVQIEEIFSFRRSRPLYSSFKGGFGHVRL.
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For Research Use Only | Not For Clinical Use.
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