Mouse Anti-Medaka thrb Antibody (MO-AB-01754R)
Cat: MO-AB-01754R
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Medaka (Oryzias latipes) |
| Clone | MO01754R |
| Specificity | This antibody binds to Medaka thrb. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. |
| Product Overview | This product is a mouse antibody against thrb. It can be used for thrb detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Thyroid hormone receptor beta; thrb |
| UniProt ID | Q766D1 |
| Protein Refseq | The length of the protein is 378 amino acids long. The sequence is show below: MSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDGKRLAKRKLIEENRERRRKEELQKTAWDRLEPTQEEWDLIRLVTEAHTTTNAQGSHWKQKRKFLSQAGGKETKPEDFGQSSVVSSPDGNKVDIEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRDQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLSSTDRIERCQEEFLLAFEHYINHRKHKVAHFWPKLLMKVTDLRMIGACHASRFLHLKVECPTELFPPLFLEVFED. |
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For Research Use Only | Not For Clinical Use.
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