Goat Anti-THRB (Center) Antibody (Cat MO-DKB-03440W)
Cat: MO-DKB-03440W
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- Product Details
Specifications
Host species | Goat (Capra hircus) |
Species Reactivity | Zebrafish (Danio rerio) |
Specificity | This antibody is not expected to cross-react with Thra. |
Immunogen | According to Uniprot Zebrafish NP_571415.1, a peptide with the sequence C-DIGSAPIVNAPEGNKVD corresponding to the internal region. |
Epitope | Center |
Format | Liquid or Lyophilized |
Buffer | Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Affinity purified |
Application Information
Application | WB, PEP-ELISA |
Application Notes | Western Blot: 2-5 ug/mL Peptide Enzyme-Linked Immunosorbent Assay: 1:32000 The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. |
Product Overview | This product is a Goat antibody against the TR beta 1/NR1A2/Thyroid Hormone Receptor beta. It can be used for TR beta 1/NR1A2/Thyroid Hormone Receptor beta detection in Western Blot, PEP-Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Thyroid hormone receptor beta; thr |
UniProt ID | J9JI02 |
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For Research Use Only | Not For Clinical Use.
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