Mouse Anti-Pig FADD Antibody (MO-AB-25750R)


Cat: MO-AB-25750R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityPig (Sus scrofa)
CloneMO25750R
SpecificityThis antibody binds to Pig FADD.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Other locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionApoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Product OverviewThis product is a mouse antibody against FADD. It can be used for FADD detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesFas; TNF receptor superfamily, member 6; Fas-associating death domain-containing protein; TNFRSF6
UniProt IDQ56VC2
Protein RefseqThe length of the protein is 211 amino acids long.
The sequence is show below: MDPFLVLLHSVSASLSSSELTELKFLCQGRVGKRKLERVQSGVDLFSVLLEQNELSPEHTALLRELLVSLRRQDLLRRLDAFEAGAAGGAAPEERDLRAAFDIICDNVGKDWRRLARQLKVSDAKIDAIEEKYPRNLTEQVRESLRVWKNSRREDAAVSHLVDALRACRLNLVADLVEEEQQARASRRESGSSDPVSLISWDEDVPGSGAS.
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For Research Use Only | Not For Clinical Use.
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