Mouse Anti-Rabbit SUMO2 Antibody (MO-AB-10144Y)
Cat: MO-AB-10144Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rabbit (Oryctolagus cuniculus) |
Clone | MO10144Y |
Specificity | This antibody binds to Rabbit SUMO2. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. Plays a role in the regulation of sumoylation status of SETX (By similarity). |
Product Overview | This product is a mouse antibody against SUMO2. It can be used for SUMO2 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Small ubiquitin-related modifier; SUMO; LOC100354027 |
UniProt ID | G1U7Y7 |
Protein Refseq | The length of the protein is 95 amino acids long. The sequence is show below: MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINESDTPAQLEMEDEDTIDVFQQQTGGVY. |
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For Research Use Only | Not For Clinical Use.
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