Rabbit Anti-RAD17 Antibody (MO-DKB-02495W)
Cat: MO-DKB-02495W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | A. thaliana (Arabidopsis thaliana) |
| Immunogen | RAD17 synthetic peptide derived from Arabidopsis AT5G66130. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Peptide affinity purified |
Application Information
| Application | WB |
| Application Notes | Western Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. |
| Product Overview | This product is a Rabbit antibody against the RAD17. It can be used for RAD17 detection in Western Blot. |
| Alternative Names | RAD17 Checkpoint Clamp Loader Component; HRAD17; R24L; Cell Cycle Checkpoint Protein (RAD17); Cell Cycle Checkpoint Protein RAD17; RAD17 Homolog (S. Pombe); RF-C Activator 1 Homolog; RF-C/Activator 1 Homolog; RAD17, ATRAD17, RADIATION SENSITIVE 17 |
| UniProt ID | Q9MBA3 |
See other products for " Rad17 "
| MO-AB-03672Y | Mouse Anti-Chicken Rad17 Antibody (MO-AB-03672Y) |
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| MO-AB-62868W | Mouse Anti-Marmoset RAD17 Antibody (MO-AB-62868W) |
| MO-AB-21057W | Mouse Anti-Chimpanzee RAD17 Antibody (MO-AB-21057W) |
| MO-DKB-00905W | Rabbit Anti-RAD17 Antibody (MO-DKB-00905W) |
| MOFY-0922-FY28 | Mouse Anti-Rad17 Antibody, IgG1 kappa (MOFY-0922-FY28) |
| MOFY-0922-FY29 | Mouse Anti-Rad17 Antibody, IgG1 kappa (MOFY-0922-FY29) |
| CBMOAB-95121FYA | Mouse Anti-Zebrafish rad17 Antibody (CBMOAB-95121FYA) |
| CBMOAB-03251CR | Mouse Anti-Yeast RAD17 Antibody (CBMOAB-03251CR) |
| CBMOAB-39745FYC | Mouse Anti-Arabidopsis RAD17 Antibody (CBMOAB-39745FYC) |
For Research Use Only | Not For Clinical Use.
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