Mouse Anti-Rad17 Antibody, IgG1 kappa (MOFY-0922-FY29)


Cat: MOFY-0922-FY29
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse
Species ReactivityS. pombe
CloneM6A173
ImmunogenRad17 fusion protein derived from Schizosaccharomyces pombe resistant
FormatLiquid or Lyophilized
BufferRefer to COA
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 95% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB

Target

IntroductionThe protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013]
Product OverviewMOFY-0922-FY29 is a mouse antibody against Rad17. It can be used for Rad17 detection in Western Blot.
Alternative NamesRAD17 Checkpoint Clamp Loader Component; HRAD17; R24L; Cell Cycle Checkpoint Protein (RAD17); Cell Cycle Checkpoint Protein RAD17; RAD17 Homolog (S. Pombe); RF-C Activator 1 Homolog; RF-C/Activator 1 Homolog#
See other products for " RAD17 "
MO-AB-18985RMouse Anti-Cattle RAD17 Antibody (MO-AB-18985R)
MO-DKB-02495WRabbit Anti-RAD17 Antibody (MO-DKB-02495W)
CBMOAB-55957FYAMouse Anti-Rhesus RAD17 Antibody (CBMOAB-55957FYA)
MO-DKB-02493WRabbit Anti-RAD17 Antibody (MO-DKB-02493W)
MO-AB-21057WMouse Anti-Chimpanzee RAD17 Antibody (MO-AB-21057W)
CBMOAB-95121FYAMouse Anti-Zebrafish rad17 Antibody (CBMOAB-95121FYA)
MO-AB-06861HMouse Anti-Frog Rad17 Antibody (MO-AB-06861H)
MO-DKB-00905WRabbit Anti-RAD17 Antibody (MO-DKB-00905W)
MOFY-0922-FY28Mouse Anti-Rad17 Antibody, IgG1 kappa (MOFY-0922-FY28)
MO-AB-62868WMouse Anti-Marmoset RAD17 Antibody (MO-AB-62868W)
For Research Use Only | Not For Clinical Use.
Online Inquiry