Mouse Anti-Sheep ADRB2 Antibody (MO-AB-14109Y)
Cat: MO-AB-14109Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Sheep (Ovis aries) |
Clone | MO14109Y |
Specificity | This antibody binds to Sheep ADRB2. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma membrane; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008] |
Product Overview | This product is a mouse antibody against ADRB2. It can be used for ADRB2 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Beta-2-adrenergic receptor; ADRB2 |
UniProt ID | B3GN13 |
Protein Refseq | The length of the protein is 418 amino acids long. The sequence is show below: MGQPGNRSVFLLAPNASHAPDQDGTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACVDLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIRMHWHRASHKEAIKCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSTSNDRTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSTDSQGRNCSTNDSLL. |
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For Research Use Only | Not For Clinical Use.
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