Mouse Anti-Sheep S100B Antibody (MO-AB-17554Y)
Cat: MO-AB-17554Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Sheep (Ovis aries) |
Clone | MO17554Y |
Specificity | This antibody binds to Sheep S100B. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Other locations; Cytosol; Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | S100 calcium binding protein B (S100B) is a protein of the S-100 protein family.S100 protein is located in the cytoplasm and nucleus of a large number of cells and participates in the regulation of many cellular processes, such as cell cycle progression and differentiation. The S100 gene includes at least 13 members clustered on chromosome 1q21. However, the gene is located at 21q22.3.S100B is glial-specific and is mainly expressed by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is expressed only by mature astrocyte subtypes that surround blood vessels and cells expressing NG2. The protein may play a role in neurite outgrowth, melanoma cell proliferation, Ca2+ flux stimulation, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing central nervous system, it acts as a neurotrophic factor and neuronal survival protein. In adult organisms, it is usually elevated due to damage to the nervous system, which makes it a potential clinical marker. |
Product Overview | This product is a mouse antibody against S100B. It can be used for S100B detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Protein S100; S100 calcium-binding protein; S100B |
UniProt ID | W5PVB6 |
Protein Refseq | The length of the protein is 92 amino acids long. The sequence is show below: MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMVTTACHEFFEHE. |
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For Research Use Only | Not For Clinical Use.
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