Mouse Anti-Cattle S100B Antibody (MO-AB-19699R)


Cat: MO-AB-19699R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO19699R
SpecificityThis antibody binds to Cattle S100B.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationCytosol; Nucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionS100 calcium binding protein B (S100B) is a protein of the S-100 protein family.S100 protein is located in the cytoplasm and nucleus of a large number of cells and participates in the regulation of many cellular processes, such as cell cycle progression and differentiation. The S100 gene includes at least 13 members clustered on chromosome 1q21. However, the gene is located at 21q22.3.S100B is glial-specific and is mainly expressed by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is expressed only by mature astrocyte subtypes that surround blood vessels and cells expressing NG2. The protein may play a role in neurite outgrowth, melanoma cell proliferation, Ca2+ flux stimulation, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing central nervous system, it acts as a neurotrophic factor and neuronal survival protein. In adult organisms, it is usually elevated due to damage to the nervous system, which makes it a potential clinical marker.
Product OverviewThis product is a mouse antibody against S100B. It can be used for S100B detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B; S100B
UniProt IDP02638
Protein RefseqThe length of the protein is 92 amino acids long.
The sequence is show below: MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFEHE.
For Research Use Only | Not For Clinical Use.
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