Rabbit Anti-S100B Antibody (MOFAB-018W)


Cat: MOFAB-018W
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Specifications

Host speciesRabbit
Species ReactivityHuman, Mouse, Rat, Zebrafish
ImmunogenRecombinant human S100B protein expressed by E. coli
FormatLiquid or Lyophilized
BufferPBS, pH 7.2, 50% glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAntigen Affinity Purified

Application Information

ApplicationELISA, WB, IP
Application NotesWB: 1:1000-2000
IP: 1:5000-10000
IF: 1:100-200
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Product OverviewThis product is a Rabbit antibody against the S100B. It can be used for S100B detection in ELISA, Western Blot, Immunoprecipitation.
Alternative NamesS100 Calcium Binding Protein B; S-100 Protein Subunit Beta; S100 Calcium Binding Protein, Beta (Neural); S100 Calcium-Binding Protein, Beta (Neural); S-100 Calcium-Binding Protein, Beta Chain; S100 Calcium-Binding Protein B; S-100 Protein Beta Chain; S100B
Gene ID6285
UniProt IDP04271
For Research Use Only | Not For Clinical Use.
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