DNA-damage-inducible transcript 3
Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
Mouse Anti-Zebrafish ddit3 Antibody (CBMOAB-73134FYA) (CAT#: CBMOAB-73134FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: C/EBP zeta
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: ddit3, DNA Damage Inducible Transcript 3
Mouse Anti-Frog ddit3 Antibody (MO-AB-02913H) (CAT#: MO-AB-02913H)
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- Host species: Mouse
- Species Reactivity: Frog (Xenopus laevis)
- Application: WB, ELISA
- Protein: C/EBP zeta
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Transcription factor GADD153, ddit3, gadd153
Mouse Anti-Elephant DDIT3 Antibody (MO-AB-00345L) (CAT#: MO-AB-00345L)
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- Host species: Mouse
- Species Reactivity: Elephant (Loxodonta africana)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, C/EBP-homologous protein 10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Rabbit DDIT3 Antibody (MO-AB-07877Y) (CAT#: MO-AB-07877Y)
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- Host species: Mouse
- Species Reactivity: Rabbit (Oryctolagus cuniculus)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, C/EBP-homologous protein 10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Cattle DDIT3 Antibody (MO-AB-11267R) (CAT#: MO-AB-11267R)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3, CHOP CHOP10 GADD153
Mouse Anti-Sheep DDIT3 Antibody (MO-AB-14925Y) (CAT#: MO-AB-14925Y)
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- Host species: Mouse
- Species Reactivity: Sheep (Ovis aries)
- Application: WB, ELISA
- Protein: C/EBP zeta
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA-damage-inducible transcript 3, DDIT3
Mouse Anti-Chimpanzee DDIT3 Antibody (MO-AB-16350W) (CAT#: MO-AB-16350W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C / EBP zeta, C / EBP-homologous protein, C / EBP-homologous protein 10, CCAAT / enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Rat Ddit3 Antibody (MO-AB-25313H) (CAT#: MO-AB-25313H)
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- Host species: Mouse
- Species Reactivity: Rat (Rattus norvegicus)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, Ddit3
Mouse Anti-Pig Ddit3 Antibody (MO-AB-25317R) (CAT#: MO-AB-25317R)
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- Host species: Mouse
- Species Reactivity: Pig (Sus scrofa)
- Application: WB, ELISA
- Protein: C/EBP zeta
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA-damage-inducible transcript 3, Ddit3, DDIT3
Mouse Anti-Dog DDIT3 Antibody (MO-AB-30117W) (CAT#: MO-AB-30117W)
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- Host species: Mouse
- Species Reactivity: Dog (Canis lupus familiaris)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C / EBP zeta, C / EBP-homologous protein, C / EBP-homologous protein 10, CCAAT / enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Ferret DDIT3 Antibody (MO-AB-34659W) (CAT#: MO-AB-34659W)
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- Host species: Mouse
- Species Reactivity: Ferret (Mustela Putorius Furo)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C / EBP zeta, C / EBP-homologous protein, C / EBP-homologous protein 10, CCAAT / enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Goat DDIT3 Antibody (MO-AB-37115W) (CAT#: MO-AB-37115W)
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- Host species: Mouse
- Species Reactivity: Goat (Capra hircus)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C / EBP zeta, C / EBP-homologous protein, C / EBP-homologous protein 10, CCAAT / enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Gorilla DDIT3 Antibody (MO-AB-38522W) (CAT#: MO-AB-38522W)
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- Host species: Mouse
- Species Reactivity: Gorilla
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C / EBP zeta, C / EBP-homologous protein, C / EBP-homologous protein 10, CCAAT / enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Hamsters DDIT3 Antibody (MO-AB-43068W) (CAT#: MO-AB-43068W)
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- Host species: Mouse
- Species Reactivity: Hamsters (Cricetinae)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C / EBP zeta, C / EBP-homologous protein, CHOP, C / EBP-homologous protein 10, CHOP-10, CCAAT / enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3, CHOP CHOP10 GADD153
Mouse Anti-Horse DDIT3 Antibody (MO-AB-44352W) (CAT#: MO-AB-44352W)
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- Host species: Mouse
- Species Reactivity: Horse (Equus caballus)
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C / EBP zeta, C / EBP-homologous protein, C / EBP-homologous protein 10, CCAAT / enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
Mouse Anti-Marmoset DDIT3 Antibody (MO-AB-54013W) (CAT#: MO-AB-54013W)
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- Host species: Mouse
- Species Reactivity: Marmoset
- Application: WB, ELISA
- Protein: DNA damage-inducible transcript 3 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, C/EBP-homologous protein 10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153, DDIT3
For Research Use Only | Not For Clinical Use.
