GTP cyclohydrolase 1

This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.

  • Mouse Anti-Arabidopsis GCH1 Antibody (CBMOAB-33899FYC) (CAT#: CBMOAB-33899FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: GTP cyclohydrolase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: GTP Cyclohydrolase 1, GTP Cyclohydrolase I, Dystonia 14, EC 3.5.4.16, GTP-CH-I, DYT5, GCH, Guanosine 5-Triphosphate Cyclohydrolase I
  • Mouse Anti-Rhesus GCH1 Antibody (CBMOAB-43465FYA) (CAT#: CBMOAB-43465FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: GCH1
  • Mouse Anti-Chicken GCH1 Antibody (MO-AB-02045Y) (CAT#: MO-AB-02045Y)

    • Host species: Mouse
    • Species Reactivity: Chicken (Gallus gallus)
    • Application: WB, ELISA
    • Protein: GTP cyclohydrolase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: GTP cyclohydrolase 1, GCH1
  • Mouse Anti-Chimpanzee GCH1 Antibody (MO-AB-16160W) (CAT#: MO-AB-16160W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: GTP cyclohydrolase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: GTP cyclohydrolase 1, GCH1
  • Mouse Anti-Marmoset GCH1 Antibody (MO-AB-55907W) (CAT#: MO-AB-55907W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: GTP cyclohydrolase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: GTP cyclohydrolase 1 isoform 1, GCH1
  • Mouse Anti-Zebrafish gch1 Antibody (CBMOAB-77680FYA) (CAT#: CBMOAB-77680FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: GTP cyclohydrolase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: gch1, GTP Cyclohydrolase 1
  • Mouse Anti-Rat Gch1 Antibody (MO-AB-25964H) (CAT#: MO-AB-25964H)

    • Host species: Mouse
    • Species Reactivity: Rat (Rattus norvegicus)
    • Application: WB, ELISA
    • Protein: GTP cyclohydrolase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: GTP cyclohydrolase 1, EC 3.5.4.16, GTP cyclohydrolase I, GTP-CH-I, Gch1, Gch
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