Mouse Anti-Zebrafish gch1 Antibody (CBMOAB-77680FYA)


Cat: CBMOAB-77680FYA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio)
CloneMO77680FYA
SpecificityThis antibody binds to Zebrafish gch1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
Product OverviewMouse Anti-Zebrafish gch1 Antibody is a mouse antibody against gch1. It can be used for gch1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Namesgch1; GTP Cyclohydrolase 1
UniProt IDE7FGQ8
Protein RefseqThe length of the protein is 251 amino acids long.
The sequence is show below: MERSKQKPVNQSEKETDGAINGHFDGRVKMPGWKAGSASGDPGSVPTSSVMESWREERTRSLEDNEMSLPSIAAAYTTILRGLGEDPQRQGLLKTPWRAATAMQFFTKGYQEKIIDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPIFGRVHIGYLPNKRVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTRDEFLTLIRS.
For Research Use Only | Not For Clinical Use.
Online Inquiry