Mouse Anti-Rat Gch1 Antibody (MO-AB-25964H)
Cat: MO-AB-25964H
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rat (Rattus norvegicus) |
| Clone | MO25964C |
| Specificity | This antibody binds to Rat Gch1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Other locations; Cytosol; Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. |
| Product Overview | This product is a mouse antibody against Gch1. It can be used for Gch1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | GTP cyclohydrolase 1; EC 3.5.4.16; GTP cyclohydrolase I; GTP-CH-I; Gch1; Gch |
| UniProt ID | P22288 |
| Protein Refseq | The length of the protein is 241 amino acids long. The sequence is show below: MEKPRGVRCTNGFPERELPRPGASRPAEKSRPPEAKGAQPADAWKAGRPRSEEDNELNLPNLAAAYSSILRSLGEDPQRQGLLKTPWRAATAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGRVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS. |
See other products for " gch1 "
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| CBMOAB-33899FYC | Mouse Anti-Arabidopsis GCH1 Antibody (CBMOAB-33899FYC) |
| CBMOAB-43465FYA | Mouse Anti-Rhesus GCH1 Antibody (CBMOAB-43465FYA) |
| MO-AB-55907W | Mouse Anti-Marmoset GCH1 Antibody (MO-AB-55907W) |
| MO-AB-16160W | Mouse Anti-Chimpanzee GCH1 Antibody (MO-AB-16160W) |
| MO-AB-02045Y | Mouse Anti-Chicken GCH1 Antibody (MO-AB-02045Y) |
For Research Use Only | Not For Clinical Use.
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