microtubule-associated protein 1 light chain 3 beta

It is observed enhanced LC3B and other autophagy-related molecules by inducing oxidative stress in OC cells using ROS-generating pro-oxidant molecules. Enhanced LC3B fails to induce autophagosome formation, possibly due to reduced ULK1 complexes. ROS-induced enhanced LC3B also increased apoptosis. Furthermore, LC3B inhibits cell adhesion molecules/mesenchymal markers, leading to anoikis. Furthermore, in vitro studies showed that ROS-dependent enhanced LC3B reduced tumor growth. Similar effects were observed with primary cells from patients. Here, we demonstrate the unique role of LC3B in in vitro/in vivo/ex vivo induction of anoikis.

  • Mouse Anti-map1lc3b Antibody (CBMOAB-85821FYA) (CAT#: CBMOAB-85821FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Fish, Frog (Xenopus), Marmoset, Medaka (Oryzias latipes)
    • Application: WB, ELISA
    • Protein: Submitted name: Map1lc3b protein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Map1lc3b protein, Microtubule-associated protein 1 light chain 3 beta, Microtubule-associated protein 1-light chain 3B, map1lc3b, MAP1-LC3
  • Rabbit Anti-map1lc3b Antibody (MOFAB-028W) (CAT#: MOFAB-028W)

    • Host species: Rabbit
    • Species Reactivity: Zebrafish, Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Fish, Frog (Xenopus), Zebrafish (Danio rerio), Marmoset, Medaka (Oryzias latipes)
    • Application: ELISA, WB
    • Protein: microtubule-associated protein 1 light chain 3 beta
    • Size: NONE
    • Conjugate: None
    • Alternative Names: map1lc3b, LC3b, Zebrafish LC3b
  • Mouse Anti-MAP1LC3B Antibody (MO-AB-15301R) (CAT#: MO-AB-15301R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Fish, Frog (Xenopus), Zebrafish (Danio rerio), Marmoset, Medaka (Oryzias latipes)
    • Application: WB, ELISA
    • Protein: Microtubule-associated proteins 1A/1B light chain 3B
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B, Microtubule-associated protein 1 lig癷?癸MAP1LC3B, MAP1ALC3 MAP1LC3
  • Mouse Anti-Map1lc3b Antibody (MO-AB-26961H) (CAT#: MO-AB-26961H)

    • Host species: Mouse
    • Species Reactivity: Rat (Rattus norvegicus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Pig (Sus scrofa), Cattle (Bos taurus), Fish, Frog (Xenopus), Zebrafish (Danio rerio), Marmoset, Medaka (Oryzias latipes)
    • Application: WB, ELISA
    • Protein: Microtubule-associated proteins 1A/1B light chain 3B
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B
  • Rabbit Anti-MAP1LC3B (N-terminal) Antibody (Cat MO-DKB-03266W) (CAT#: MO-DKB-03266W)

    • Host species: Rabbit
    • Species Reactivity: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Ba, Cattle (Bos taurus), Dog (Canis lupus familiaris), Primate, Zebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fish, Frog (Xenopus), Marmoset, Medaka (Oryzias latipes)
    • Application: WB, EM, FC, IB, IF, IHC, IHC-Fr, IHC-P, IP, KD, KO
    • Protein: Submitted name: Map1lc3b protein
    • Size: 100µL
    • Conjugate: Unconjugated
    • Alternative Names: Map1lc3b protein, Microtubule-associated protein 1 light chain 3 beta, Microtubule-associated protein 1-light chain 3B, map1lc3b, MAP1-LC3
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