Rabbit Anti-map1lc3b Antibody (MOFAB-028W)
Cat: MOFAB-028W
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| MOFAB-028W | Polyclonal | Zebrafish, Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Fish, Frog (Xenopus), Zebrafish (Danio rerio), Marmoset, Medaka (Oryzias latipes) | ELISA, WB | 100 µg | |||
| MO-AB-21877W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO21877W | 100 µg | ||
| MO-AB-58601W | Monoclonal | Marmoset | WB, ELISA | MO58601W | 100 µg | ||
| MO-AB-00863R | Monoclonal | Medaka (Oryzias latipes) | WB, ELISA | MO00863R | 100 µg | ||
| MO-AB-27126R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO27126R | 100 µg | ||
| MO-AB-04992H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO04992C | 100 µg | ||
| MO-NAB-00358W | Monoclonal | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Fish, Frog (Xenopus), Zebrafish (Danio rerio) | WB, FC, FC-IC, IF, IHC, IHC-Fr, IHC-P, IP, KO | NW0284 | 100 µg |
Specifications
| Host species | Rabbit |
| Species Reactivity | Zebrafish, Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Fish, Frog (Xenopus), Zebrafish (Danio rerio), Marmoset, Medaka (Oryzias latipes) |
| Immunogen | Peptides from zebrafish LC3b sequences |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7.2, 50% glycerol |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Antigen Affinity Purified |
Application Information
| Application | ELISA, WB |
| Application Notes | WB: 1:1000-2000 IP: 3ug/Sample IF: 1:100-200 The optimal dilution should be determined by the end user. |
Target
| Introduction | It is observed enhanced LC3B and other autophagy-related molecules by inducing oxidative stress in OC cells using ROS-generating pro-oxidant molecules. Enhanced LC3B fails to induce autophagosome formation, possibly due to reduced ULK1 complexes. ROS-induced enhanced LC3B also increased apoptosis. Furthermore, LC3B inhibits cell adhesion molecules/mesenchymal markers, leading to anoikis. Furthermore, in vitro studies showed that ROS-dependent enhanced LC3B reduced tumor growth. Similar effects were observed with primary cells from patients. Here, we demonstrate the unique role of LC3B in in vitro/in vivo/ex vivo induction of anoikis. |
| Product Overview | This product is a Rabbit antibody against the map1lc3b. It can be used for map1lc3b detection in ELISA, Western Blot. |
| Alternative Names | map1lc3b; LC3b; Zebrafish LC3b |
See other products for " MAP1LC3B "
| MO-DKB-03266W | Rabbit Anti-MAP1LC3B (N-terminal) Antibody (Cat MO-DKB-03266W) |
| MO-AB-15301R | Mouse Anti-MAP1LC3B Antibody (MO-AB-15301R) |
| CBMOAB-85821FYA | Mouse Anti-map1lc3b Antibody (CBMOAB-85821FYA) |
| MO-AB-26961H | Mouse Anti-Map1lc3b Antibody (MO-AB-26961H) |
For Research Use Only | Not For Clinical Use.
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