Connect with Us at the Upcoming Events

Creative Biolabs is excited to greet you at the upcoming international conferences. Meet our team at the 13th Annual World ADC San Diego and the 13th Annual World Multispecific Summit in September, the 10th Annual Immuno-Oncology Summit in October, and the Antibody Engineering & Therapeutics (US) 2022 in December for expert consultation on your drug discovery projects. Shoot an email to arrange an in-person meeting!

Rabbit Anti-map1lc3b Antibody (MOFAB-028W)

Cat: MOFAB-028W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

  • Product Details


Host speciesRabbit
Species ReactivityZebrafish
ImmunogenPeptides from zebrafish LC3b sequences
BufferPBS, pH 7.2, 50% glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
PurificationAntigen Affinity Purified

Application Information

ApplicationELISA, WB
Application NotesWB: 1:1000-2000

IP: 3ug/Sample

IF: 1:100-200
The optimal dilution should be determined by the end user.


IntroductionIt is observed enhanced LC3B and other autophagy-related molecules by inducing oxidative stress in OC cells using ROS-generating pro-oxidant molecules. Enhanced LC3B fails to induce autophagosome formation, possibly due to reduced ULK1 complexes. ROS-induced enhanced LC3B also increased apoptosis. Furthermore, LC3B inhibits cell adhesion molecules/mesenchymal markers, leading to anoikis. Furthermore, in vitro studies showed that ROS-dependent enhanced LC3B reduced tumor growth. Similar effects were observed with primary cells from patients. Here, we demonstrate the unique role of LC3B in in vitro/in vivo/ex vivo induction of anoikis.
Product OverviewThis product is a Rabbit antibody against the map1lc3b. It can be used for map1lc3b detection in ELISA, Western Blot.
Alternative Namesmap1lc3b; LC3b; Zebrafish LC3b
For Research Use Only | Not For Clinical Use.

Online Inquiry