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- Product Details
|Immunogen||Peptides from zebrafish LC3b sequences|
|Buffer||PBS, pH 7.2, 50% glycerol|
|Regulatory Status||For Research Use Only|
|Storage||Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.|
|Purification||Antigen Affinity Purified|
|Application Notes||WB: 1:1000-2000|
The optimal dilution should be determined by the end user.
|Introduction||It is observed enhanced LC3B and other autophagy-related molecules by inducing oxidative stress in OC cells using ROS-generating pro-oxidant molecules. Enhanced LC3B fails to induce autophagosome formation, possibly due to reduced ULK1 complexes. ROS-induced enhanced LC3B also increased apoptosis. Furthermore, LC3B inhibits cell adhesion molecules/mesenchymal markers, leading to anoikis. Furthermore, in vitro studies showed that ROS-dependent enhanced LC3B reduced tumor growth. Similar effects were observed with primary cells from patients. Here, we demonstrate the unique role of LC3B in in vitro/in vivo/ex vivo induction of anoikis.|
|Product Overview||This product is a Rabbit antibody against the map1lc3b. It can be used for map1lc3b detection in ELISA, Western Blot.|
|Alternative Names||map1lc3b; LC3b; Zebrafish LC3b|
See other products for " MAP1LC3B "
|MO-NAB-00358W||Rabbit Anti-MAP1LC3B Antibody (AA 1-100)|
|MO-AB-26961H||Mouse Anti-Rat Map1lc3b Antibody (MO-AB-26961H)|
|MO-AB-15301R||Mouse Anti-Cattle MAP1LC3B Antibody (MO-AB-15301R)|
|MO-AB-58601W||Mouse Anti-Marmoset MAP1LC3B Antibody (MO-AB-58601W)|
|MO-AB-00863R||Mouse Anti-Medaka MAP1LC3B Antibody (MO-AB-00863R)|
|MO-AB-21877W||Mouse Anti-Chimpanzee MAP1LC3B Antibody (MO-AB-21877W)|
|MO-AB-27126R||Mouse Anti-Pig MAP1LC3B Antibody (MO-AB-27126R)|
|CBMOAB-85821FYA||Mouse Anti-Zebrafish map1lc3b Antibody (CBMOAB-85821FYA)|
|MO-DKB-03266W||Rabbit Anti-MAP1LC3B (N-terminal) Antibody (Cat MO-DKB-03266W)|
|MO-AB-04992H||Mouse Anti-Frog map1lc3b Antibody (MO-AB-04992H)|