Rabbit Anti-map1lc3b Antibody (MOFAB-028W)
Cat: MOFAB-028W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Rabbit |
| Species Reactivity | Zebrafish |
| Immunogen | Peptides from zebrafish LC3b sequences |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7.2, 50% glycerol |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Antigen Affinity Purified |
Application Information
| Application | ELISA, WB |
| Application Notes | WB: 1:1000-2000 IP: 3ug/Sample IF: 1:100-200 The optimal dilution should be determined by the end user. |
Target
| Introduction | It is observed enhanced LC3B and other autophagy-related molecules by inducing oxidative stress in OC cells using ROS-generating pro-oxidant molecules. Enhanced LC3B fails to induce autophagosome formation, possibly due to reduced ULK1 complexes. ROS-induced enhanced LC3B also increased apoptosis. Furthermore, LC3B inhibits cell adhesion molecules/mesenchymal markers, leading to anoikis. Furthermore, in vitro studies showed that ROS-dependent enhanced LC3B reduced tumor growth. Similar effects were observed with primary cells from patients. Here, we demonstrate the unique role of LC3B in in vitro/in vivo/ex vivo induction of anoikis. |
| Product Overview | This product is a Rabbit antibody against the map1lc3b. It can be used for map1lc3b detection in ELISA, Western Blot. |
| Alternative Names | map1lc3b; LC3b; Zebrafish LC3b |
See other products for " map1lc3b "
| MO-AB-04992H | Mouse Anti-Frog map1lc3b Antibody (MO-AB-04992H) |
| MO-AB-15301R | Mouse Anti-Cattle MAP1LC3B Antibody (MO-AB-15301R) |
| MO-NAB-00358W | Rabbit Anti-MAP1LC3B Antibody (AA 1-100) |
| MO-AB-26961H | Mouse Anti-Rat Map1lc3b Antibody (MO-AB-26961H) |
| MO-DKB-03266W | Rabbit Anti-MAP1LC3B (N-terminal) Antibody (Cat MO-DKB-03266W) |
| MO-AB-00863R | Mouse Anti-Medaka MAP1LC3B Antibody (MO-AB-00863R) |
| MO-AB-58601W | Mouse Anti-Marmoset MAP1LC3B Antibody (MO-AB-58601W) |
| CBMOAB-85821FYA | Mouse Anti-Zebrafish map1lc3b Antibody (CBMOAB-85821FYA) |
| MO-AB-27126R | Mouse Anti-Pig MAP1LC3B Antibody (MO-AB-27126R) |
| MO-AB-21877W | Mouse Anti-Chimpanzee MAP1LC3B Antibody (MO-AB-21877W) |
For Research Use Only | Not For Clinical Use.
Online Inquiry