Mouse Anti-Chimpanzee CASP3 Antibody (MO-AB-16426W)


Cat: MO-AB-16426W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityChimpanzee (Pan troglodytes)
CloneMO16426W
SpecificityThis antibody binds to Chimpanzee CASP3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationCytosol; Nucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Product OverviewMouse Anti-Chimpanzee CASP3 Antibody is a mouse antibody against CASP3. It can be used for CASP3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCaspase 3, apoptosis-related cysteine peptidase; CASP3
UniProt IDK7D0A9
Protein RefseqThe length of the protein is 277 amino acids long.
The sequence is show below: MENTENSVDSKSIKNLEPKIIHGSQSMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH.
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For Research Use Only | Not For Clinical Use.
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