Rabbit Anti-d2hgdh Antibody (MO-DKB-00206W)
Cat: MO-DKB-00206W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Zebrafish (Danio rerio) |
| Specificity | This antibody is binds to Zebrafish d2hgdh. |
| Immunogen | Recombinant zebrafish D-2-hydroxyglutarate dehydrogenase, mitochondrial protein |
| Epitope | The epitope is in the AA 56-533 of d2hgdh. |
| Format | Liquid or Lyophilized |
| Buffer | PBS pH 7.4, 50% Glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 95% was determined by SDS-PAEG |
| Purification | Purified with G affinity chromatography |
Application Information
| Application | ELISA |
Target
| Introduction | This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.D2HGDH (D-2-Hydroxyglutarate Dehydrogenase) is a Protein Coding gene. Diseases associated with D2HGDH include D-2-Hydroxyglutaric Aciduria 1 and 2-Hydroxyglutaric Aciduria. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Pyruvate metabolism and Citric Acid (TCA) cycle. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and oxidoreductase activity, acting on CH-OH group of donors.Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate. |
| Product Overview | This product is a rabbit antibody against the AA 56-533 of the d2hgdh. It can be used for d2hgdh detection in Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | D-2-hydroxyglutarate dehydrogenase, mitochondrial; EC 1.1.99.-; d2hgd |
| UniProt ID | A1L258 |
See other products for " D2HGDH "
| CBMOAB-22470FYB | Mouse Anti-Rice D2HGDH Antibody (CBMOAB-22470FYB) |
| MO-AB-20099W | Mouse Anti-Chimpanzee D2HGDH Antibody (MO-AB-20099W) |
| CBMOAB-72836FYA | Mouse Anti-Zebrafish d2hgdh Antibody (CBMOAB-72836FYA) |
| CBMOAB-40357FYA | Mouse Anti-Rhesus D2HGDH Antibody (CBMOAB-40357FYA) |
| CBMOAB-27341FYC | Mouse Anti-Arabidopsis D2HGDH Antibody (CBMOAB-27341FYC) |
| MO-AB-53876W | Mouse Anti-Marmoset D2HGDH Antibody (MO-AB-53876W) |
| MO-AB-11161R | Mouse Anti-Cattle D2HGDH Antibody (MO-AB-11161R) |
For Research Use Only | Not For Clinical Use.
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