Mouse Anti-Rhesus D2HGDH Antibody (CBMOAB-40357FYA)
Cat: CBMOAB-40357FYA
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta) |
Clone | MO40357FYA |
Specificity | This antibody binds to Rhesus D2HGDH. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Mitochondrion |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.D2HGDH (D-2-Hydroxyglutarate Dehydrogenase) is a Protein Coding gene. Diseases associated with D2HGDH include D-2-Hydroxyglutaric Aciduria 1 and 2-Hydroxyglutaric Aciduria. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Pyruvate metabolism and Citric Acid (TCA) cycle. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and oxidoreductase activity, acting on CH-OH group of donors.Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate. |
Product Overview | Mouse Anti-Rhesus D2HGDH Antibody is a mouse antibody against D2HGDH. It can be used for D2HGDH detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | D2HGDH |
UniProt ID | F6YN82 |
Protein Refseq | The length of the protein is 505 amino acids long. The sequence is show below: APGAAGSWGRPVGPLARRGCCSAPGTPEVPLTRERYPVRRLPFSTVSEQDLAAFERIVPGGVVTDPEALQAPNVDWIRTLRGSSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNKVLSFHSVSGILVCQAGCVLEELSHYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTILDCLTSLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRYLHLASPVQESPFYVLIETSGSNAGHDAEKLGSFLEHALGSGLVTDGTMATDQTKVKMLWALRERIAEALSRDGYVYKYDLSLPVERLYDIVTDVRARLGPHAKHVVGYGHLGDGNLHLNVTAEAFSPSLLGALEPHVYEWTARQQGSVSAEHGVGFRKRDVLGYSKPPEALQLMQQLKALLDPKGILNPYKTLPSQA. |
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For Research Use Only | Not For Clinical Use.
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