Mouse Anti-FOS Antibody
Cat: MO-NAB-00322W
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Human (Homo sapiens), Rat (Rattus norvegicus), Monkey (Macaca mulatta) |
| Clone | NW0250 |
| Specificity | This antibody is binds to Human FOS and has cross reactivity with Rat, Monkey. |
| Immunogen | The purified recombinant human FOS protein fragment eXenopuspressed in E. coli. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7.4, 50% Glycerol. |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Affinity purified |
Application Information
| Application | ELISA, WB |
| Application Notes | Western Blot: 1:500-1:5000 |
Target
| Introduction | In the field of molecular biology and genetics, c-Fos is a proto-oncogene and a homolog of the human retroviral oncogene v-fos. It was first discovered in rat fibroblasts, and it is a transformed gene of FBJ MSV (Finkel-Biskis-Kingsins murine osteosarcoma virus) (Curran and Tech, 1982). It is part of a larger family of Fos transcription factors, including c-Fos, FosB, Fra-1 and Fra-2. It has been mapped to chromosome region 14q21→q31. c-Fos encodes a 62 kDa protein that forms a heterodimer with c-jun (part of the transcription factor Jun family), resulting in the formation of an AP-1 (activator protein-1) complex, which is located in AP- 1 Specific sites bind DNA in the promoter and enhancer regions of target genes, and convert extracellular signals into changes in gene expression. It plays an important role in many cell functions and has been found to be overexpressed in many cancers. |
| Product Overview | This product is a Mouse antibody against the FOS. It can be used for FOS detection in Enzyme-Linked Immunosorbent Assay, Western Blot. |
| Alternative Names | FOS; AP-1; C-p55; Fos proto-oncogene; AP-1 transcription factor subunit |
| Gene ID | 2553 (Human); 14281 (Mouse) |
| UniProt ID | P01100 (Human); P01101 (Mouse) |
See other products for " FOS "
| MO-AB-08763W | Mouse Anti-Cat FOS Antibody (MO-AB-08763W) |
| MO-AB-43144W | Mouse Anti-Hamsters FOS Antibody (MO-AB-43144W) |
| MOFY-1222-FY61 | Rabbit Anti-fos Antibody (MOFY-1222-FY61) |
| MO-AB-15293Y | Mouse Anti-Sheep FOS Antibody (MO-AB-15293Y) |
| MO-AB-25877H | Mouse Anti-Rat Fos Antibody (MO-AB-25877H) |
| CBMOAB-76762FYA | Mouse Anti-Zebrafish fos Antibody (CBMOAB-76762FYA) |
| MO-AB-12673R | Mouse Anti-Cattle FOS Antibody (MO-AB-12673R) |
| MO-AB-20534W | Mouse Anti-Chimpanzee FOS Antibody (MO-AB-20534W) |
| MO-AB-55602W | Mouse Anti-Marmoset FOS Antibody (MO-AB-55602W) |
| MO-AB-03664H | Mouse Anti-Frog fos Antibody (MO-AB-03664H) |
For Research Use Only | Not For Clinical Use.
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