Mouse Anti-Sheep FOS Antibody (MO-AB-15293Y)


Cat: MO-AB-15293Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivitySheep (Ovis aries)
CloneMO15293Y
SpecificityThis antibody binds to Sheep FOS.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionIn the field of molecular biology and genetics, c-Fos is a proto-oncogene and a homolog of the human retroviral oncogene v-fos. It was first discovered in rat fibroblasts, and it is a transformed gene of FBJ MSV (Finkel-Biskis-Kingsins murine osteosarcoma virus) (Curran and Tech, 1982). It is part of a larger family of Fos transcription factors, including c-Fos, FosB, Fra-1 and Fra-2. It has been mapped to chromosome region 14q21→q31. c-Fos encodes a 62 kDa protein that forms a heterodimer with c-jun (part of the transcription factor Jun family), resulting in the formation of an AP-1 (activator protein-1) complex, which is located in AP- 1 Specific sites bind DNA in the promoter and enhancer regions of target genes, and convert extracellular signals into changes in gene expression. It plays an important role in many cell functions and has been found to be overexpressed in many cancers.
Product OverviewThis product is a mouse antibody against FOS. It can be used for FOS detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesV-fos FBJ murine osteosarcoma viral oncogene-like protein; FOS
UniProt IDC8BKC1
Protein RefseqThe length of the protein is 380 amino acids long. The sequence is show below: MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDYCTDLAVSSANFIPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGVPTPSAGAYSRAGVMKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLSGGLPEAATPESEEAFTLPLLNDPEPKPSVEPVKSVGSMELKAEPFDDFMFPVSSRPSGSETARSVPDMDLSGSFYAADWEPLHGGSLGMGPMATELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL.
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For Research Use Only | Not For Clinical Use.
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