Mouse Anti-Frog fgb Antibody (MO-AB-03571H)
Cat: MO-AB-03571H
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Frog (Xenopus laevis) |
| Clone | MO03571C |
| Specificity | This antibody binds to Frog fgb. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Extracellular region or secreted |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Product Overview | This product is a mouse antibody against fgb. It can be used for fgb detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Fibrinogen B-beta subunit; LOC397825 protein; fgb; LOC397825 |
| UniProt ID | Q91589 |
| Protein Refseq | The length of the protein is 488 amino acids long. The sequence is show below: MRVLLLFALCVSAVWCSSDYDEDDVDDAAVIKSDNATASVDARGHRPVSRGREPVPTQRPAPPPISGGSYRGRPTKAPVKGQKKEATEYPDAGGCKHAYEELGTLCPTGCELRTTLLKQERNVKTAINDVRGRVETLAQSANNVYRYTTVLGQKIKENQQQTLDNQNVVNEYNLELEEQYTFIKDNIDTKIPSNIRILRQVLENLRSKIQKLETAIATQVENCRSPCVTTCPIPVVSGKECEEIYRKGGETSEMYLIQPDSFFRPFKVYCDMATHDGGWTVIQNRQDGSVGFGRTWDSYKSGFGNIAANGGKGICDMPGEFWLGNEKISQLTNLGATEALFEMEDWDGAKVTAQYTGFTVQNEANKYQLSVSGYKGTAGNALMDGASQLKGENRTMTIHNGMFFSTFDRDNDGWQHSDPNKQCSKEDGGGWWYNRCHAANPNGRYYWGGYYTWDMAKHGTDDGVVWMNWKDSWYSMKKMSIKIRPYFN. |
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For Research Use Only | Not For Clinical Use.
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