Mouse Anti-Horse FGB Antibody (MO-AB-44732W)
Cat: MO-AB-44732W
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Horse (Equus caballus) |
Clone | MO44732W |
Specificity | This antibody binds to Horse FGB. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Other locations; Extracellular region or secreted; Plasma membrane; Endoplasmic reticulum |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Product Overview | Mouse Anti-Horse FGB Antibody is a mouse antibody against FGB. It can be used for FGB detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Fibrinogen beta chain; FGB |
UniProt ID | F6PH38 |
Protein Refseq | The length of the protein is490 amino acids long. The sequence is show below: QRMVSWNFQKFKTMKLLFLLLLCVSVVRSQALDYDHEVTFDARSHRPLDKKREEPLSLKPAPPPISGPGYRPRPAKVAANKKKVERKAPDAGGCVHADPDLGVLCPTGCQLQDTLVKQERSVRNSVNELSHNVESISQSSSSNFQYITALKEMWKKREKQLKDNENVVGEYSSELEKHQLYIDETVNSNVPTNIRVLRSILENLRSKIQKLESDVSAQMEYCRNPCTVSCNIPVVSGRECEEVIRNGGETSEMYLIQPDRSAKPYRVYCDMTTESGGWTVIQNRQDGSVDFGRKWDPYKQGFGNIATNADGKKYCGLPGEYWLGNDKISQLTMMGPTVLLIEMEDWRGDKVKALYEGFTVKGEGDKYQLSVGKYKGTAGNALVDGASQLVGENRTMTIHNGMYFSTYDRDNDGWTTTDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYSWDMAKHGTDDGVVWMNWKGSWYSMKKISMKIRPYFPQQ. |
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For Research Use Only | Not For Clinical Use.
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