Mouse Anti-Medaka IL-17A Antibody (MO-AB-00751R)

Cat: MO-AB-00751R
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  • Product Details


Host speciesMouse (Mus musculus)
Species ReactivityMedaka (Oryzias latipes)
SpecificityThis antibody binds to Medaka IL-17A.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationExtracellular region or secreted

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.


IntroductionIL-17A (IL-17A, IL17A) is a potent pro-inflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8+ T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and resistance to bacteria and fungi. IL-17A acts on a wide range of cell types to induce the expression of cytokines, chemokines and metalloproteinases. Therefore, secretion of IL-17A promotes the inflammatory response, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased IL-17A expression is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It has also been linked to asthma, psoriasis, cancer and transplant rejection.
Product OverviewThis product is a mouse antibody against IL-17A. It can be used for IL-17A detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesInterleukin-17A/F-3; IL-17A/F-3
UniProt IDE3WEA9
Protein RefseqThe length of the protein is 157 amino acids long.
For Research Use Only | Not For Clinical Use.
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