Rabbit Anti-NCSTN Antibody (MO-DKB-01346W)
Cat: MO-DKB-01346W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Dog (Canis lupus familiaris), Rhesus (Macaca mulatta) |
| Immunogen | Recombinant protein containing sequences in the central region of human Nicastrin. |
| Epitope | The epitope is in the Center of NCSTN. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7, 20% Glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Affinity purified |
| Cellular Localization | Membrane, Single-pass type I membrane protein (Potential), Melanosome |
Application Information
| Application | WB, IF |
| Application Notes | Western Blot 1:500-1:3000 Immunocytochemistry/Immunofluorescence 1:100-1:1000 |
Target
| Introduction | This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Feb 2014] |
| Product Overview | This product is a Rabbit antibody against the Center of the NCSTN. It can be used for NCSTN detection in Western Blot, Immunofluorescence. |
| Alternative Names | Nicastrin; Anterior Pharynx-Defective 2; ATAG1874; KIAA0253; |
| Gene ID | 23385 |
| UniProt ID | Q92542 |
See other products for " NCSTN "
| MO-AB-16445R | Mouse Anti-Cattle NCSTN Antibody (MO-AB-16445R) |
| MO-AB-13943W | Mouse Anti-Chimpanzee NCSTN Antibody (MO-AB-13943W) |
| MO-AB-31898W | Mouse Anti-Dog NCSTN Antibody (MO-AB-31898W) |
| MO-AB-03057Y | Mouse Anti-Chicken NCSTN Antibody (MO-AB-03057Y) |
| CBMOAB-52350FYA | Mouse Anti-Rhesus NCSTN Antibody (CBMOAB-52350FYA) |
| CBMOAB-88530FYA | Mouse Anti-Zebrafish ncstn Antibody (CBMOAB-88530FYA) |
| MO-AB-59825W | Mouse Anti-Marmoset NCSTN Antibody (MO-AB-59825W) |
For Research Use Only | Not For Clinical Use.
Online Inquiry