Mouse Anti-Zebrafish ncstn Antibody (CBMOAB-88530FYA)
Cat: CBMOAB-88530FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Zebrafish (Danio rerio) |
| Clone | MO88530FYA |
| Specificity | This antibody binds to Zebrafish ncstn. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
| Product Overview | Mouse Anti-Zebrafish ncstn Antibody is a mouse antibody against ncstn. It can be used for ncstn detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Nicastrin; ncst |
| UniProt ID | Q5XLR3 |
| Protein Refseq | The length of the protein is 707 amino acids long. The sequence is show below: MENLISINCVQLLITALFYTCISCSSVEQKIYVELNKTAPCVRLLNATHQIGCQSSISGDTGVVHVLESESDLDWILSAGPHPPYMVIMETAFFNRSVMLSMKNSSRVAGVAVIISKAGLAEHFSPHTTCPNQNTGVYSAGSEFANCNGTVWNPLGNGLSYEDFTFPVFALKDENQTQVIRKCYEDHNLRVNGSAPQYPLCAMQLFSHMHAVTDTVTCMRRTDLQNKFSINPEILCDPLSDYNVWTSIRPLNNSARGHAENESVVIAAVRLDGRSFFWEEAPAAEGTVSAIVTLLAAIHALYPVIQEAPPLRNIFFTFFQGEAFDYIGSSRMVFDMERNQFVMDLDNVHSMLEIGQVGLRGGRDVWIHSDPVSRRNSSMEKQVSEMIKDVNSSAAGLNINLQEPSVSQPLPPSSFQRFLRVRPIPGLVLTDHEKAFNNRYYESMYDDAENLNVSYPPNLTPDEQLVYPTDAAKSLAEVATLVARSLYTQAGGEQNNLSNITADATMVSQLLYGFLVQKNNSWFRSLLPPEITKKGGSSILSSGPPQFYIGLGPRLQSPVHSVTLFVQYILANLTGNVTNLTESQCQNPKELSGENKDLYSYFWVSGPSSGNSSADPLCVRASVRLSKAVSPAFELLQYGSSDYSTWTESRWKSIRARIFLVASRELEMLTLGVGVAVLLLSLLVTYFISSKAELLFSSARETPTTTY. |
See other products for " NCSTN "
| MO-AB-16445R | Mouse Anti-Cattle NCSTN Antibody (MO-AB-16445R) |
| MO-AB-13943W | Mouse Anti-Chimpanzee NCSTN Antibody (MO-AB-13943W) |
| MO-AB-31898W | Mouse Anti-Dog NCSTN Antibody (MO-AB-31898W) |
| CBMOAB-52350FYA | Mouse Anti-Rhesus NCSTN Antibody (CBMOAB-52350FYA) |
| MO-AB-59825W | Mouse Anti-Marmoset NCSTN Antibody (MO-AB-59825W) |
| MO-AB-03057Y | Mouse Anti-Chicken NCSTN Antibody (MO-AB-03057Y) |
| MO-DKB-01346W | Rabbit Anti-NCSTN Antibody (MO-DKB-01346W) |
For Research Use Only | Not For Clinical Use.
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