Mouse Anti-Rabbit TLR4 Antibody (MO-AB-10228Y)
Cat: MO-AB-10228Y
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rabbit (Oryctolagus cuniculus) |
| Clone | MO10228Y |
| Specificity | This antibody binds to Rabbit TLR4. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane; Other locations; Golgi apparatus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Product Overview | This product is a mouse antibody against TLR4. It can be used for TLR4 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Toll-like receptor; TLR4 |
| UniProt ID | G1SH24 |
| Protein Refseq | The length of the protein is 839 amino acids long. The sequence is show below: MMPRLRLAGTLVPAMAFLSYLRPEIWEPCVEVVPNITYQCMEKNLYKIPDNIPFSTKNLDLSFNLLEHLGSHSFLHVSELHFLDLSRCKIHTIEDDAYQGLKNLSTLILTGNPIQSLSPQAFSGLSNLQKLVAVETHLTSLGDFPIGHLKTLKELNVAHNLIHSFSIPDYFSNLSSLEHLDLSNNKIQSIYHKDLRVLHQMPLGTLSLDLSLNPIDFIQPGAFEAIRLHELILKSNFKSTNIMKICIQGLSGLEVHRLVLGEFKNERNMKNFDKSALEGLCNLAIEEFRLAYIDDLEGNITDLFDCLENVSVMALVHMYIDNQEIFPKDFSWKSLEFINCEFSENIFFLKLSSLRRLIFTANKGVRTFPELNTPSLEFLDISNNGLSLQSCCSVNSLRLTQLKHLNLSFNGVITMTSNFVGLEQLEHLYFQHSNLRNINEFSIFLSLNNLLYLDISYTHIRVAFRGIFDGLYSLRVLKMAGNAFQDNRLLNIFTEMTSLTTLDLSSCQLEQVYQGAFESLPRLESLNMSHNNLLVLDTLTYKCLYSLQVLDLSFNHIGNITEPGQQHFPSNLTLLHLTKNAFVCDCEHQIFMQWIKDQRRLLVEVEQMVCITPPNMPVLSFTNATCQISKTIISVSVFSVLVVSFAVVLVYKFYFPLMLLVGRRKYGRGESVYDAFVIYSSQDEDWVRNELVKNLEEGVPPFRLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSHAGIIFIVLQKVEKSLLRQRVELYRLLSRNTYLEWEDTVLGRHIFWRRLRKALLDGKTLSPEGMARAENNQQEAMTLI. |
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For Research Use Only | Not For Clinical Use.
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