Rabbit Anti-TARDBP (AA 350-414) Antibody (Cat MO-DKB-03142W)


Cat: MO-DKB-03142W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Chicken (Gallus gallus), Primate, Frog (Xenopus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human TDP-43/TARDBP and has cross reactivity with Mouse, Chicken, Primate, Frog, Zebrafish TDP-43/TARDBP.
ImmunogenA synthetic peptide of the C-terminal region of human TARDBP protein [residues 350-414]. [Swiss-Prot: Q13148]
EpitopeAA 350-414
FormatLiquid or Lyophilized
BufferPBS
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified
Cellular LocalizationNuclear

Application Information

ApplicationWB, ELISA, IF, IHC, IHC-P
Application NotesWestern Blot: 0.5-2 ug/mL
Immunocytochemistry/Immunofluorescence: 1:100-1:1000
Immunohistochemistry: 1:250
Immunohistochemistry-Paraffin: 1:250
The optimal dilution should be determined by the end user.

Target

IntroductionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Product OverviewThis product is a Rabbit antibody against the TDP-43/TARDBP. It can be used for TDP-43/TARDBP detection in Western Blot, Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesTAR DNA binding protein; tardb
UniProt IDQ802C7
For Research Use Only | Not For Clinical Use.
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