Rabbit Anti-TARDBP Antibody (MOF032922W139)


Cat: MOF032922W139
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Specifications

Host speciesRabbit
Species ReactivityHuman, Mouse, Rat, Zebrafish
SpecificityTDP43 Antibody detects endogenous levels of total TDP43
ImmunogenA synthetic peptide derived from human TDP43
FormatLiquid or Lyophilized
BufferPBS pH 7.4, 150mM NaCl, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 95% was determined by SDS-PAGE
PurificationAffinity Chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, IHC-P, ICC/IF, IP, FC
Application NotesWB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/50 FC: 1/200
The optimal dilution should be determined by the end user.

Target

IntroductionTDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).
Alternative NamesALS10; TAR DNA binding protein 43; TARDBP; TDP43;
Gene ID23435
UniProt IDQ13148
For Research Use Only | Not For Clinical Use.
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