Rabbit Anti-TARDBP Antibody (AA 350-390)
Cat: MO-NAB-00408W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
| Clone | NW0333 |
| Specificity | This antibody is binds to Human TARDBP and has cross reactivity with Mouse, Rat, Zebrafish. |
| Immunogen | Synthetic peptide within human TDP-43/TARDBP aa 350-390. |
| Epitope | The epitope is in the AA 350-390 of TARDBP. |
| Format | Liquid or Lyophilized |
| Buffer | TBS, pH7.4, 1% BSA, 40% Glycerol. |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Protein A purified |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, FC, IF, IHC, IHC-P, IP |
| Application Notes | Western Blot: 1:500-1:5000 Flow Cytometry: 1:50-1:100 Immunofluorescence: 1:100-1:500 Immunohistochemistry-Paraffin: 1:50-1:200 |
Target
| Introduction | TAR DNA-binding protein 43 (TDP-43, response to DNA-binding protein 43 kDa) is a protein encoded by the TARDBP gene in humans. TDP-43 has been shown to bind DNA and RNA, and has multiple functions in transcriptional suppression, pre-mRNA splicing and translation regulation. Recent work has characterized the binding sites of the entire transcriptome, revealing that thousands of RNAs in neurons are bound by TDP-43. TDP-43 was originally identified as a transcriptional repressor, which binds to chromosomally integrated transactivation response element (TAR) DNA and inhibits HIV-1 transcription. It is reported that it can also regulate the alternative splicing of CFTR gene and apoA-II gene. |
| Product Overview | This product is a Rabbit antibody against the AA 350-390 of the TARDBP. It can be used for TARDBP detection in Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation. |
| Alternative Names | TARDBP; ALS10; TDP-43; TAR DNA binding protein |
| Gene ID | 23435(Human); 230908(Mouse); 298648(Rat) |
| UniProt ID | Q13148(Human); Q921F2(Mouse) |
See other products for " TARDBP "
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| MO-DKB-03142W | Rabbit Anti-TARDBP (AA 350-414) Antibody (Cat MO-DKB-03142W) |
| CBMOAB-08627FYB | Mouse Anti-Zebrafish tardbp Antibody (CBMOAB-08627FYB) |
| MO-AB-23607W | Mouse Anti-Chimpanzee TARDBP Antibody (MO-AB-23607W) |
| CBMOAB-00304FYA | Rabbit Anti-Mouse TARDBP Antibody (CBMOAB-00304FYA) |
| MO-AB-04292Y | Mouse Anti-Chicken TARDBP Antibody (MO-AB-04292Y) |
| MO-AB-65849W | Mouse Anti-Marmoset TARDBP Antibody (MO-AB-65849W) |
| MOFY-1222-FY102 | Rabbit Anti-TARDBP Antibody (MOFY-1222-FY102) |
For Research Use Only | Not For Clinical Use.
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