Rabbit Anti-tardbp (AA 250-350, clone ms2109-048) Antibody (Cat MO-DKB-03640W)
Cat: MO-DKB-03640W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
| Clone | ms2109-048 |
| Specificity | This antibody is binds to Human TDP43 and has cross reactivity with Mouse, Rat, Zebrafish TDP43. |
| Immunogen | Human TDP43 is between 250-350 amino acids |
| Epitope | AA 250-350 |
| Format | Liquid or Lyophilized |
| Buffer | TBS, pH 7.4, 1% BSA, 40% Glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Protein A purified |
Application Information
| Application | WB, FC, IHC-P, IF, IHC |
| Application Notes | Western Blot: 1:300-1000 Flow Cytometry: 1:20-100 Immunohistochemistry-Paraffin 1:200-400 Immunofluorescence/Immunocytochemistry: 1:50-200 The optimal dilution should be determined by the end user. |
Target
| Introduction | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. |
| Product Overview | This product is a Rabbit antibody against the TDP43. It can be used for TDP43 detection in Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence, Immunohistochemistry. |
| Alternative Names | TAR DNA binding protein; tardb; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; POLR2A |
| UniProt ID | Q802C7 |
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For Research Use Only | Not For Clinical Use.
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