Rabbit Anti-IDH1 Antibody (MO-DKB-01757W)
Cat: MO-DKB-01757W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | A. thaliana (Arabidopsis thaliana) |
| Immunogen | IDH1 synthetic peptide derived from Arabidopsis AT4G35260. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Peptide affinity purified |
Application Information
| Application | WB |
| Application Notes | Western Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user. |
Target
| Introduction | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Product Overview | This product is a Rabbit antibody against the IDH1. It can be used for IDH1 detection in Western Blot. |
| Alternative Names | Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic; IDH1, Isocitrate dehydrogenase(NAD) 1, Isocitrate dehydrogenase I, IDH-I |
| UniProt ID | Q8LFC0 |
See other products for " IDH1 "
| MO-AB-31214W | Mouse Anti-Dog IDH1 Antibody (MO-AB-31214W) |
| MO-AB-15701Y | Mouse Anti-Sheep IDH1 Antibody (MO-AB-15701Y) |
| MO-AB-26463R | Mouse Anti-Pig IDH1 Antibody (MO-AB-26463R) |
| CBMOAB-01822CR | Mouse Anti-Yeast IDH1 Antibody (CBMOAB-01822CR) |
| MO-NAB-00176W | Mouse Anti-Rhesus IDH1 Antibody (MO-NAB-00176W) |
| CBMOAB-80247FYA | Mouse Anti-Zebrafish idh1 Antibody (CBMOAB-80247FYA) |
| CBMOAB-05230HCB | Mouse Anti-C. elegans IDH1 Antibody (CBMOAB-05230HCB) |
| MO-AB-45088W | Mouse Anti-Horse IDH1 Antibody (MO-AB-45088W) |
| MO-NAB-00344W | Mouse Anti-IDH1 Antibody |
| MO-DKB-00658W | Rabbit Anti-IDH1 Antibody (MO-DKB-00658W) |
For Research Use Only | Not For Clinical Use.
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