Mouse Anti-Rhesus IDH1 Antibody (MO-NAB-00176W)
Cat: MO-NAB-00176W
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Rhesus (Macaca mulatta), Sheep (Ovis aries) |
| Clone | NW0094 |
| Immunogen | Recombinant protein contains the sequence in the central region of human IDH1. The exact order is proprietary. |
| Format | Liquid or Lyophilized |
| Buffer | PBS |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Protein G purified |
Application Information
| Application | WB, IF, IP, KD, KO |
| Application Notes | WB: 1/500-1/10000 IF: 1/100-1/1000 IP: 1/100-1/1000 |
Target
| Introduction | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013] |
| Product Overview | Mouse Anti-Rhesus IDH1 (clone NW0094) Antibody (MO-NAB-00176W) is a Mouse antibody against the epitope of the Isocitrate Dehydrogenase 1/IDH1. It can be used for Isocitrate Dehydrogenase 1/IDH1 detection in Western Blot, Immunofluorescence, Immunoprecipitation, KD, KO. |
| Alternative Names | Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic |
| Gene ID | 3417 |
| UniProt ID | O75874 |
See other products for " IDH1 "
| MO-NAB-00514W | Goat Anti-IDH1 Antibody |
| MO-AB-15701Y | Mouse Anti-Sheep IDH1 Antibody (MO-AB-15701Y) |
| MO-NAB-00344W | Mouse Anti-IDH1 Antibody |
| MO-DKB-01757W | Rabbit Anti-IDH1 Antibody (MO-DKB-01757W) |
| MO-AB-41844W | Mouse Anti-Guinea pig IDH1 Antibody (MO-AB-41844W) |
| MO-AB-34917W | Mouse Anti-Ferret IDH1 Antibody (MO-AB-34917W) |
| MO-DKB-03942W | Goat Anti-IDH1 (Center) Antibody (Cat MO-DKB-03942W) |
| MO-AB-26463R | Mouse Anti-Pig IDH1 Antibody (MO-AB-26463R) |
| CBMOAB-01822CR | Mouse Anti-Yeast IDH1 Antibody (CBMOAB-01822CR) |
| MO-AB-08433Y | Mouse Anti-Rabbit IDH1 Antibody (MO-AB-08433Y) |
For Research Use Only | Not For Clinical Use.
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