Goat Anti-IDH1 (Center) Antibody (Cat MO-DKB-03942W)
Cat: MO-DKB-03942W
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- Product Details
Specifications
Host species | Goat (Capra hircus) |
Species Reactivity | S.cerevisiae |
Specificity | This antibody is binds to S.cerevisiae IDH1. |
Epitope | Center |
Format | Liquid or Lyophilized |
Buffer | Tris saline, pH 7.3, 0.5% BSA |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Affinity purified |
Application Information
Application | Pep-ELISA, WB |
Application Notes | Western Blot: 0.3-1 ug/mL Enzyme-Linked Immunosorbent Assay: 1:16000. The optimal dilution should be determined by the end user. |
Target
Introduction | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Product Overview | This product is a Goat antibody against the IDH1. It can be used for IDH1 detection in Pep-Enzyme-Linked Immunosorbent Assay, Western Blot. |
Alternative Names | Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; EC 1.1.1.41; Isocitric dehydrogenase; NAD(+)-specific ICDH; IDH1; YNL037C |
UniProt ID | P28834 |
See other products for " IDH1 "
MO-AB-23293H | Mouse Anti-Mallard IDH1 Antibody (MO-AB-23293H) |
MO-AB-15701Y | Mouse Anti-Sheep IDH1 Antibody (MO-AB-15701Y) |
MO-NAB-00514W | Goat Anti-IDH1 Antibody |
MO-DKB-00658W | Rabbit Anti-IDH1 Antibody (MO-DKB-00658W) |
MO-AB-45088W | Mouse Anti-Horse IDH1 Antibody (MO-AB-45088W) |
MO-DKB-01757W | Rabbit Anti-IDH1 Antibody (MO-DKB-01757W) |
MO-NAB-00176W | Mouse Anti-Rhesus IDH1 Antibody (MO-NAB-00176W) |
MO-AB-04431H | Mouse Anti-Frog idh1 Antibody (MO-AB-04431H) |
MO-AB-31214W | Mouse Anti-Dog IDH1 Antibody (MO-AB-31214W) |
MO-AB-09136W | Mouse Anti-Cat IDH1 Antibody (MO-AB-09136W) |
For Research Use Only | Not For Clinical Use.
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