Sheep Anti-NR3C1 Antibody (MOFAB-122W)
Cat: MOFAB-122W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Sheep |
| Species Reactivity | Human, Monkey |
| Specificity | The antibody reacts specifically with monkey and human glucocorticoid receptors. |
| Immunogen | A peptide consisting of amino acids 150-175 of the squirrel monkey glucocorticoid receptor conjugated to diphtheria toxoid. The sequence is identical in the human glucocorticoid receptor except for 2 amino acids (underlined): N-terminus - APKEKEFPKTHSDVSSEQ-QNLKGQTG-NH2 - C-terminus. |
| Format | Liquid or Lyophilized |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | WB |
| Application Notes | WB:1:500-1:1000 The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). |
| Product Overview | The NR3C1 antibody is used as Hormones and Serum Protein Antibodies. |
| Alternative Names | Nuclear Receptor Subfamily 3 Group C Member 1; Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor); Glucocorticoid Receptor; GRL; GR; Nuclear Receptor Subfamily 3, Group C, Member 1 |
| Gene ID | 2908 |
| UniProt ID | P04150 |
See other products for " NR3C1 "
| MO-AB-15330W | Mouse Anti-Chimpanzee NR3C1 Antibody (MO-AB-15330W) |
| CBMOAB-89903FYA | Mouse Anti-Zebrafish nr3c1 Antibody (CBMOAB-89903FYA) |
| CBMOAB-52949FYA | Mouse Anti-Rhesus NR3C1 Antibody (CBMOAB-52949FYA) |
| MO-AB-60301W | Mouse Anti-Marmoset NR3C1 Antibody (MO-AB-60301W) |
| MO-AB-01075R | Mouse Anti-Medaka nr3c1 Antibody (MO-AB-01075R) |
| MO-AB-05763H | Mouse Anti-Frog nr3c1 Antibody (MO-AB-05763H) |
| MO-AB-45811W | Mouse Anti-Horse NR3C1 Antibody (MO-AB-45811W) |
| MO-NAB-00236W | Mouse Anti-Yeast NR3C1 Antibody (MO-NAB-00236W) |
| MO-AB-08997Y | Mouse Anti-Rabbit NR3C1 Antibody (MO-AB-08997Y) |
| MO-NAB-00478W | Rabbit Anti-NR3C1 Antibody |
For Research Use Only | Not For Clinical Use.
Online Inquiry