Mouse Anti-Rhesus BEST1 Antibody (MO-AB-01288W)
Cat: MO-AB-01288W
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta) |
| Clone | MO01288W |
| Specificity | This antibody binds to Rhesus BEST1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms. |
| Product Overview | Mouse Anti-Rhesus BEST1 Antibody is a mouse antibody against BEST1. It can be used for BEST1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Bestrophin-1 isoform 1; BEST1 |
| UniProt ID | H9F2T2 |
| Protein Refseq | The length of the protein is 348 amino acids long. The sequence is show below: QVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNEPEPHPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDKEDAHTGIIGRFLGLQSHDHHPPGANSRTKLLWPKRESLLHEGLPKNHKAVKQNVRGLEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPPEPSVLSKLHSVTGIDTKDKSLKTVSSGAKNSSELLSGSDGALMEHPEVSHVRRKTVEFNLTDMPEIPENHLKEPLELSTTNIHATLKDHVDPYWALENRDEAHS. |
See other products for " BEST1 "
| MORAB-027F | Anti-BEST1 Antibody (Cat MORAB-027F), Mouse IgG |
| CBMOAB-67627FYA | Mouse Anti-Zebrafish best1 Antibody (CBMOAB-67627FYA) |
| MO-AB-51847W | Mouse Anti-Marmoset BEST1 Antibody (MO-AB-51847W) |
| CBMOAB-02375FYA | Mouse Anti-D. melanogaster Best1 Antibody (CBMOAB-02375FYA) |
| MO-AB-08058R | Mouse Anti-Cattle BEST1 Antibody (MO-AB-08058R) |
| CBMOAB-00900HCB | Mouse Anti-C. elegans BEST1 Antibody (CBMOAB-00900HCB) |
| MO-AB-29237W | Mouse Anti-Dog BEST1 Antibody (MO-AB-29237W) |
| MO-AB-24121R | Mouse Anti-Pig BEST1 Antibody (MO-AB-24121R) |
For Research Use Only | Not For Clinical Use.
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