Rabbit Anti-CASP3 Antibody (MOFAB-004W)


Cat: MOFAB-004W
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Specifications

Host speciesRabbit
Species ReactivityZebrafish
ImmunogenPeptide corresponding to zebrafish Casapase-3
FormatLiquid or Lyophilized
BufferPBS, pH 7.2, 50% glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAntigen Affinity Purified

Application Information

ApplicationELISA, WB, IP, IF
Application NotesWB: 1:1000-2000
IP: 1:5000-10000
IF: 1:100-200
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Product OverviewThis product is a Rabbit antibody against the CASP3. It can be used for CASP3 detection in ELISA, Western Blot, Immunoprecipitation, Immunofluorescence.
Alternative NamesCaspase 3; Caspase 3, Apoptosis-Related Cysteine Peptidase; Caspase 3, Apoptosis-Related Cysteine Protease; SREBP Cleavage Activity 1; Cysteine Protease CPP32; Protein Yama; EC 3.4.22.56; Apopain; CASP-3; Caspase-3
Gene ID140621
UniProt IDQ98UI8
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For Research Use Only | Not For Clinical Use.
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