Mouse Anti-Horse CASP3 Antibody (MO-AB-43906W)


Cat: MO-AB-43906W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityHorse (Equus caballus)
CloneMO43906W
SpecificityThis antibody binds to Horse CASP3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Cytosol; Nucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Product OverviewMouse Anti-Horse CASP3 Antibody is a mouse antibody against CASP3. It can be used for CASP3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCaspase-3-like protein; CASP3
UniProt IDF7A730
Protein RefseqThe length of the protein is277 amino acids long.
The sequence is show below: MENSKISVDSKSIKNSETKILHGSKSMDSGISLDSSYKMDYPEMGLCIIINNKNFHKSTGMASRSGTDVDAANLRETFTNLKYEVRNKNDLTGEEIVALMRSVSKEDHSKRSSFICVLLSHGEEGIIFGTNGPIDLKKLTCFFKGDCCRSLAGKPKLFIIQACRGTELDSGIETDSGIEDDMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKLYAHKLELMHILTRVNRKVAMEFESYCLDPTFHGKKQIPCIVSMLTKELYFYH.
For Research Use Only | Not For Clinical Use.
Online Inquiry