Infectious Disease

Supported by in-house scientists and first-class technical platform, Creative Biolabs provides a full range of high-quality infectious disease-related products and services to facilitate your project success.

Background

Infection is the reaction that the invasion of an organism's body tissues by disease-causing agents, and host tissues to the infectious agents and the toxins they produce.

Infectious disease, also known as communicable disease or transmissible disease. There are many organisms live on or in our bodies. Sometimes may cause disease even though they are normally harmless or helpful.

Research Area of Infectious Disease in Different Species

• Zebrafish

The zebrafish model has been used to study the disease pathogenesis of M. fortuitum infections. Research has reported that according to the creation of fluorescent M. fortuitum, morpholino injection and CFTR knockdown, zebrafish microinjection, infection, live imaging, zebrafish embryos from granulomas as early as 2 days post-infection and the transient macrophage depletion in zebrafish led to rapid embryo death with increased bacterial extracellular cord formation.

• Caenorhabditis elegans (C. elegans)

The model of C. elegans has been used to analyze a panel pf lab strains of E.feacium with deletions of targeted virulence factor "in vivo". This study used the method of C. elegans enterococcus pathogenesis assays, colony forming unit assay genomic analysis, microscopy and RNA interference protocol. The results showed that C. elegans is a high throughput infection model for studying the pathogenesis of E.feacium and removal of certain virulence factors was sufficient to affect the virulence of E.feacium. Besides, multiple deletions were required to affect pathogenesis, suggesting that host-pathogen interaction are multifactorial.

• Drosophila melanogaster (D. melanogaster)

Proper insight into host-pathogen interactions were used D. melanogaster as the model. In vivo D. melanogaster studies enabled the identification of humoral and cell-mediated host defense factors against a wide array of intracellular and extracellular pathogens.

As a reliable provider in the antibody products, Creative Biolabs supplys a collection of high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In this infectious disease-focused module you will find antibodies to those targets involved in infectious disease. For further details, please feel free to contact us.

Our provided featured target antibody products include the followings, but not limited to: